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1 reference

Research article 2016 Reviewed MVA Hackathon 2026 — BUB1B

Induction of heat shock proteins in differentiated human neuronal cells following co-application of celastrol and arimoclomol

Catherine A.S. Deane, Ian R. Brown Cell Stress and Chaperones

Few effective therapies exist for the treatment of neurodegenerative diseases that have been characterized as protein misfolding disorders. Upregulation of heat shock proteins (Hsps) mitigates against the accumulation of… abstract via OpenAlex

Evidence snapshot note: Deane and Brown — conditional heat-shock co-induction. Model: Differentiated human SH-SY5Y cells; arimoclomol plus celastrol. Where: Figures 2–5; not a BUBR1 study · cited by MVA-ARI-007

  • Heat shock
  • Celastrol
  • Arimoclomol
  • Hspa1a (Hsp70-1)

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KBot · Guía de investigación

Respuestas preescritas · Evidencia enlazada

KBot

Hola, soy KBot, la guía de investigación de BioLab. Puedo explicar los casos de investigación, el Literature Workspace, el grafo de evidencia y las herramientas de análisis, y dónde termina cada uno. Elige un tema abajo. Son explicaciones preescritas, no una consulta de IA en vivo.

Información de investigación, no consejo médico individual. No se envía ni se guarda ningún mensaje.